Which statement about glioblastoma is NOT correct?

Which statement about glioblastoma is NOT correct?

• A. It is the most common and aggressive CNS tumor.
• B. It frequently presents with focal deficits depending on location.
• C. It is usually benign and slow-growing.
• D. It can cause seizures and mental status changes.

Answer: (C)

Glioblastoma is a malignant, highly aggressive primary brain tumor. Its cells infiltrate surrounding brain tissue and drive rapid growth, with areas of necrosis and new blood vessel formation. This aggressive behavior explains why patients often have focal neurological deficits depending on tumor location, as well as seizures and changes in mental status. Imaging typically shows a ring-enhancing lesion with central necrosis due to disrupted blood-brain barrier. Despite treatment that includes maximal safe resection followed by radiotherapy with temozolomide, prognosis remains poor. Therefore, the statement that it is usually benign and slow-growing is not correct. It is the most common and aggressive CNS tumor and is frequently associated with focal deficits, seizures, and mental status changes.

Glioblastoma is a malignant, highly aggressive primary brain tumor. Its cells infiltrate surrounding brain tissue and drive rapid growth, with areas of necrosis and new blood vessel formation. This aggressive behavior explains why patients often have focal neurological deficits depending on tumor location, as well as seizures and changes in mental status. Imaging typically shows a ring-enhancing lesion with central necrosis due to disrupted blood-brain barrier. Despite treatment that includes maximal safe resection followed by radiotherapy with temozolomide, prognosis remains poor.

Therefore, the statement that it is usually benign and slow-growing is not correct. It is the most common and aggressive CNS tumor and is frequently associated with focal deficits, seizures, and mental status changes.