Which medication is specifically used on-demand for premature ejaculation?

Which medication is specifically used on-demand for premature ejaculation?

• A. Sertraline
• B. Dapoxetine
• C. Fluoxetine
• D. Paroxetine

Answer: (B)

On-demand control of premature ejaculation is best achieved with a short-acting medication designed specifically for use before sex. Dapoxetine is that drug: a short-acting SSRI with rapid onset, taken a few hours before anticipated intercourse. Its effects rise quickly and it clears from the body quickly, which helps reduce ejaculation latency during a single sexual encounter without causing lingering effects the next day. This makes it practical for on-demand use. In contrast, other SSRIs such as sertraline, fluoxetine, and paroxetine are typically used as daily, long-term therapy for PE. They have longer half-lives and take weeks to achieve full effect, and they can produce ongoing sexual side effects or withdrawal symptoms if stopped suddenly. While they may delay ejaculation, they aren’t formulated for on-demand dosing, which is why dapoxetine is the preferred option for this specific use case.

On-demand control of premature ejaculation is best achieved with a short-acting medication designed specifically for use before sex. Dapoxetine is that drug: a short-acting SSRI with rapid onset, taken a few hours before anticipated intercourse. Its effects rise quickly and it clears from the body quickly, which helps reduce ejaculation latency during a single sexual encounter without causing lingering effects the next day. This makes it practical for on-demand use.

In contrast, other SSRIs such as sertraline, fluoxetine, and paroxetine are typically used as daily, long-term therapy for PE. They have longer half-lives and take weeks to achieve full effect, and they can produce ongoing sexual side effects or withdrawal symptoms if stopped suddenly. While they may delay ejaculation, they aren’t formulated for on-demand dosing, which is why dapoxetine is the preferred option for this specific use case.