Which medication is commonly used to treat diabetic neuropathy?

Which medication is commonly used to treat diabetic neuropathy?

• A. Lisinopril
• B. Metformin
• C. Gabapentin
• D. Bevacizumab

Answer: (C)

Diabetic neuropathy often presents with nerve pain that responds to medications dampening neuropathic signaling. Gabapentin fits this use because it binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, reducing the release of excitatory neurotransmitters and decreasing abnormal nerve firing that causes pain. Lisinopril helps control blood pressure and offers kidney protection in diabetes but doesn’t address neuropathic pain. Metformin improves blood glucose control rather than treating nerve pain. Bevacizumab inhibits VEGF and is used for certain cancers and eye diseases, not neuropathic symptoms. So gabapentin is the medication commonly used to treat diabetic neuropathy.

Diabetic neuropathy often presents with nerve pain that responds to medications dampening neuropathic signaling. Gabapentin fits this use because it binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, reducing the release of excitatory neurotransmitters and decreasing abnormal nerve firing that causes pain. Lisinopril helps control blood pressure and offers kidney protection in diabetes but doesn’t address neuropathic pain. Metformin improves blood glucose control rather than treating nerve pain. Bevacizumab inhibits VEGF and is used for certain cancers and eye diseases, not neuropathic symptoms. So gabapentin is the medication commonly used to treat diabetic neuropathy.