Which is a common clinical finding in primary aldosteronism?

Which is a common clinical finding in primary aldosteronism?

• A. Hypotension
• B. Hypernatremia
• C. Refractory hypertension
• D. Hyperkalemia

Answer: (C)

Excess aldosterone drives sodium and water reabsorption, expanding extracellular volume and raising blood pressure. In primary aldosteronism, this often translates to hypertension that is difficult to control despite multiple antihypertensive medications. This tendency toward resistant or refractory hypertension is the characteristic clinical clue. Remember that aldosterone also causes potassium loss, so hypokalemia is common, not hyperkalemia. Hypernatremia is not a defining feature, as sodium balance can vary. Hypotension would not fit the typical picture.

Excess aldosterone drives sodium and water reabsorption, expanding extracellular volume and raising blood pressure. In primary aldosteronism, this often translates to hypertension that is difficult to control despite multiple antihypertensive medications. This tendency toward resistant or refractory hypertension is the characteristic clinical clue.

Remember that aldosterone also causes potassium loss, so hypokalemia is common, not hyperkalemia. Hypernatremia is not a defining feature, as sodium balance can vary. Hypotension would not fit the typical picture.