Which is a common adverse effect of intranasal corticosteroids?

Which is a common adverse effect of intranasal corticosteroids?

• A. Hypertension
• B. Nasal irritation or dryness
• C. Candidiasis
• D. Adrenal suppression

Answer: (B)

Intranasal corticosteroids mainly cause local effects because the medication acts directly on the nasal mucosa. The most common adverse effect is nasal irritation or dryness, which patients often notice as a burning sensation, crusting, or mild discomfort after spraying. This reflects the drying and irritant effect on the delicate nasal lining. Systemic adverse effects like adrenal suppression or hypertension are unlikely with intranasal use due to limited systemic absorption. Candidiasis is more commonly linked to inhaled corticosteroids that involve the oropharynx, though it can rarely occur with nasal sprays if there is significant mucosal exposure.

Intranasal corticosteroids mainly cause local effects because the medication acts directly on the nasal mucosa. The most common adverse effect is nasal irritation or dryness, which patients often notice as a burning sensation, crusting, or mild discomfort after spraying. This reflects the drying and irritant effect on the delicate nasal lining.

Systemic adverse effects like adrenal suppression or hypertension are unlikely with intranasal use due to limited systemic absorption. Candidiasis is more commonly linked to inhaled corticosteroids that involve the oropharynx, though it can rarely occur with nasal sprays if there is significant mucosal exposure.