Which factor is associated with increased risk of ovarian cancer?

Which factor is associated with increased risk of ovarian cancer?

• A. Regular exercise
• B. Breastfeeding
• C. Oral contraceptives
• D. Obesity

Answer: (D)

Obesity increases ovarian cancer risk because excess adipose tissue creates a pro-inflammatory, insulin-resistant environment and raises estrogen levels, especially after menopause. These hormonal and metabolic changes can promote ovarian carcinogenesis and tumor growth. In contrast, regular exercise helps reduce risk through weight management and anti-inflammatory effects, while breastfeeding and oral contraceptives lower risk by suppressing ovulation and altering hormonal exposure. So the factor tied to higher risk in this set is obesity.

Obesity increases ovarian cancer risk because excess adipose tissue creates a pro-inflammatory, insulin-resistant environment and raises estrogen levels, especially after menopause. These hormonal and metabolic changes can promote ovarian carcinogenesis and tumor growth. In contrast, regular exercise helps reduce risk through weight management and anti-inflammatory effects, while breastfeeding and oral contraceptives lower risk by suppressing ovulation and altering hormonal exposure. So the factor tied to higher risk in this set is obesity.