Which diagnostic test is commonly used to obtain tissue for histologic evaluation in suspected endometrial cancer?

Which diagnostic test is commonly used to obtain tissue for histologic evaluation in suspected endometrial cancer?

• A. Endometrial biopsy
• B. Chest X-ray
• C. Serum glucose
• D. Mammography

Answer: (A)

When endometrial cancer is suspected, confirming the diagnosis hinges on obtaining tissue from the uterine lining for microscopic examination. An endometrial biopsy is commonly performed in the outpatient setting to sample the endometrium, providing tissue for histologic analysis that reveals malignant cells and helps determine the cancer’s type and grade. The other options don’t yield endometrial tissue or provide diagnostic histology for the uterus: chest X-ray looks for lung issues, serum glucose is a metabolic measure, and mammography examines breast tissue. In some cases, if office sampling is nondiagnostic, procedures like dilation and curettage or hysteroscopy with directed biopsy may be used to obtain tissue.

When endometrial cancer is suspected, confirming the diagnosis hinges on obtaining tissue from the uterine lining for microscopic examination. An endometrial biopsy is commonly performed in the outpatient setting to sample the endometrium, providing tissue for histologic analysis that reveals malignant cells and helps determine the cancer’s type and grade. The other options don’t yield endometrial tissue or provide diagnostic histology for the uterus: chest X-ray looks for lung issues, serum glucose is a metabolic measure, and mammography examines breast tissue. In some cases, if office sampling is nondiagnostic, procedures like dilation and curettage or hysteroscopy with directed biopsy may be used to obtain tissue.