Riboflavin deficiency presents with which signs as part of the Oral-Ocular-Genital syndrome?

Riboflavin deficiency presents with which signs as part of the Oral-Ocular-Genital syndrome?

• A. Magenta colored tongue, angular cheilitis, photophobia, corneal lesions, scrotal dermatitis
• B. Glossitis with angular stomatitis
• C. Pellagra-like dermatitis
• D. Night blindness

Answer: (A)

Riboflavin deficiency (vitamin B2) causes ariboflavinosis, a mucocutaneous and ocular syndrome often described as Oral-Ocular-Genital. The magenta-colored tongue and angular cheilitis reflect the classic mucosal involvement, while photophobia and corneal lesions show the ocular component, and scrotal dermatitis indicates genital involvement. This full set of signs—mouth, eyes, and genital skin—is characteristic of riboflavin deficiency, making this option the best match. In contrast, glossitis with angular stomatitis can occur but lacks the ocular and genital findings; pellagra-like dermatitis points to niacin deficiency, and night blindness is associated with vitamin A deficiency.

Riboflavin deficiency (vitamin B2) causes ariboflavinosis, a mucocutaneous and ocular syndrome often described as Oral-Ocular-Genital. The magenta-colored tongue and angular cheilitis reflect the classic mucosal involvement, while photophobia and corneal lesions show the ocular component, and scrotal dermatitis indicates genital involvement. This full set of signs—mouth, eyes, and genital skin—is characteristic of riboflavin deficiency, making this option the best match. In contrast, glossitis with angular stomatitis can occur but lacks the ocular and genital findings; pellagra-like dermatitis points to niacin deficiency, and night blindness is associated with vitamin A deficiency.