In the history of a patient with suspected type 2 diabetes, which combination of symptoms is most characteristic?

In the history of a patient with suspected type 2 diabetes, which combination of symptoms is most characteristic?

• A. Weight loss and fatigue with nocturia.
• B. Polyuria and polydipsia, with weight gain and fungal infections.
• C. Abdominal pain and vomiting.
• D. Seizures and coma.

Answer: (B)

Polyuria and polydipsia arise from hyperglycemia causing osmotic diuresis, a hallmark of diabetes. In type 2 diabetes, insulin resistance often leads to weight gain rather than loss, and high glucose levels in tissues and urine promote mucosal and cutaneous Candida infections. So this combination—from increased urination and thirst to weight gain and fungal infections—best fits the typical history of type 2 diabetes. The other symptom clusters align more with GI illness or acute metabolic crises rather than the common chronic presentation.

Polyuria and polydipsia arise from hyperglycemia causing osmotic diuresis, a hallmark of diabetes. In type 2 diabetes, insulin resistance often leads to weight gain rather than loss, and high glucose levels in tissues and urine promote mucosal and cutaneous Candida infections. So this combination—from increased urination and thirst to weight gain and fungal infections—best fits the typical history of type 2 diabetes. The other symptom clusters align more with GI illness or acute metabolic crises rather than the common chronic presentation.