Condyloma acuminatum is most commonly caused by infection with which virus?

Condyloma acuminatum is most commonly caused by infection with which virus?

• A. HSV
• B. VZV
• C. CMV
• D. HPV

Answer: (D)

Genital warts (condyloma acuminatum) are caused most often by human papillomavirus infection, especially low-risk types 6 and 11. These HPV types infect the squamous epithelium, leading to epithelial proliferation and the characteristic soft, cauliflower-like genital lesions. Transmission is through sexual contact, and vaccination that covers 6, 11, 16, and 18 reduces the risk of both warts and HPV-related cancers. Other viruses listed produce different genital manifestations—herpes simplex virus causes painful ulcers and vesicles, varicella-zoster virus causes chickenpox or shingles, and CMV is typically a concern in immunocompromised patients without causing warts.

Genital warts (condyloma acuminatum) are caused most often by human papillomavirus infection, especially low-risk types 6 and 11. These HPV types infect the squamous epithelium, leading to epithelial proliferation and the characteristic soft, cauliflower-like genital lesions. Transmission is through sexual contact, and vaccination that covers 6, 11, 16, and 18 reduces the risk of both warts and HPV-related cancers. Other viruses listed produce different genital manifestations—herpes simplex virus causes painful ulcers and vesicles, varicella-zoster virus causes chickenpox or shingles, and CMV is typically a concern in immunocompromised patients without causing warts.