CMV-related disease in immunocompromised patients can include which of the following?

CMV-related disease in immunocompromised patients can include which of the following?

• A. Osteoarthritis
• B. Hepatitis C
• C. Psoriasis
• D. CMV retinitis

Answer: (D)

In immunocompromised patients, CMV often reactivates and causes end-organ disease, with retinitis being a classic manifestation. CMV retinitis occurs when the virus damages the retina, leading to vision changes and characteristic retinal necrosis with hemorrhages, especially in advanced HIV/AIDS or after transplantation. This is why the option describing CMV retinitis best fits. The other choices—degenerative joint disease (osteoarthritis), hepatitis C, and psoriasis—are not typical CMV end-organ diseases in this setting; they involve different etiologies and pathologies.

In immunocompromised patients, CMV often reactivates and causes end-organ disease, with retinitis being a classic manifestation. CMV retinitis occurs when the virus damages the retina, leading to vision changes and characteristic retinal necrosis with hemorrhages, especially in advanced HIV/AIDS or after transplantation. This is why the option describing CMV retinitis best fits. The other choices—degenerative joint disease (osteoarthritis), hepatitis C, and psoriasis—are not typical CMV end-organ diseases in this setting; they involve different etiologies and pathologies.