CA-125 is a biomarker that may be elevated in which cancers?

CA-125 is a biomarker that may be elevated in which cancers?

• A. CEA
• B. AFP
• C. hCG
• D. CA-125

Answer: (D)

CA-125 is a tumor marker most closely linked to epithelial ovarian cancer. Elevations are most commonly seen with ovarian malignancies, and it’s used to help monitor treatment response and detect recurrence. The other markers point to different cancers or conditions: CEA is associated with colorectal and some GI cancers; AFP with hepatocellular carcinoma and certain germ cell tumors; hCG with pregnancy and germ cell tumors like choriocarcinoma. So among the options, CA-125 best fits the cancers that elevate this biomarker, particularly ovarian cancer.

CA-125 is a tumor marker most closely linked to epithelial ovarian cancer. Elevations are most commonly seen with ovarian malignancies, and it’s used to help monitor treatment response and detect recurrence. The other markers point to different cancers or conditions: CEA is associated with colorectal and some GI cancers; AFP with hepatocellular carcinoma and certain germ cell tumors; hCG with pregnancy and germ cell tumors like choriocarcinoma. So among the options, CA-125 best fits the cancers that elevate this biomarker, particularly ovarian cancer.