Among the following demographics, which is most commonly affected by Budd-Chiari syndrome according to the material?

Among the following demographics, which is most commonly affected by Budd-Chiari syndrome according to the material?

• A. Men in their 50s
• B. Women around 25 years old
• C. Children under 10
• D. Elderly with diabetes

Answer: (B)

Budd-Chiari syndrome is hepatic venous outflow obstruction usually caused by thrombosis in a hypercoagulable state. The demographic pattern most commonly seen is women around 25 years old, often in the setting of estrogen exposure such as oral contraceptive use or recent pregnancy. Estrogen increases coagulability and, together with pregnancy-related hypercoagulability, makes young women of reproductive age the group most at risk. That’s why this demographic is the best fit. The other groups—men in their 50s, children under 10, and elderly individuals with diabetes—don’t align with the typical risk profile and are less commonly affected.

Budd-Chiari syndrome is hepatic venous outflow obstruction usually caused by thrombosis in a hypercoagulable state. The demographic pattern most commonly seen is women around 25 years old, often in the setting of estrogen exposure such as oral contraceptive use or recent pregnancy. Estrogen increases coagulability and, together with pregnancy-related hypercoagulability, makes young women of reproductive age the group most at risk. That’s why this demographic is the best fit. The other groups—men in their 50s, children under 10, and elderly individuals with diabetes—don’t align with the typical risk profile and are less commonly affected.