After radical orchiectomy for a low-grade seminoma, additional therapy may include what?

After radical orchiectomy for a low-grade seminoma, additional therapy may include what?

• A. Radical orchiectomy with or without chemotherapy or radiotherapy
• B. Observation after orchiectomy
• C. Chemotherapy only
• D. Radiation therapy only

Answer: (D)

Seminomas are highly radiosensitive, so after removing the testicle, targeted radiation to the retroperitoneal (para-aortic) lymph nodes is an effective adjuvant approach to lower relapse risk in localized disease. This makes radiation therapy alone the best fit among the options provided for additional therapy after orchiectomy in a low-grade seminoma. While some patients may be managed with surveillance or with chemotherapy in other contexts, adjuvant radiotherapy remains a standard, straightforward option to reduce recurrence after the primary tumor is removed.

Seminomas are highly radiosensitive, so after removing the testicle, targeted radiation to the retroperitoneal (para-aortic) lymph nodes is an effective adjuvant approach to lower relapse risk in localized disease. This makes radiation therapy alone the best fit among the options provided for additional therapy after orchiectomy in a low-grade seminoma. While some patients may be managed with surveillance or with chemotherapy in other contexts, adjuvant radiotherapy remains a standard, straightforward option to reduce recurrence after the primary tumor is removed.